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Peer-Reviewed Publications

  1. Drummond DA and Wilke CO. Mistranslation-induced protein misfolding as a dominant constraint on coding-sequence evolution. Cell 2008 Jul 25; 134(2) 341-52. doi:10.1016/j.cell.2008.05.042 pmid:18662548. PubMed HubMed [Drummond-Cell-2008]
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  2. Li Y, Drummond DA, Sawayama AM, Snow CD, Bloom JD, and Arnold FH. A diverse family of thermostable cytochrome P450s created by recombination of stabilizing fragments. Nat Biotechnol 2007 Sep; 25(9) 1051-6. doi:10.1038/nbt1333 pmid:17721510. PubMed HubMed [Li-NBT-2007]
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  3. Bloom JD, Drummond DA, Arnold FH, and Wilke CO. Structural determinants of the rate of protein evolution in yeast. Mol Biol Evol 2006 Sep; 23(9) 1751-61. doi:10.1093/molbev/msl040 pmid:16782762. PubMed HubMed [Bloom-MBE-2006]
  4. Wilke CO and Drummond DA. Population genetics of translational robustness. Genetics 2006 May; 173(1) 473-81. doi:10.1534/genetics.105.051300 pmid:16489231. PubMed HubMed [Wilke-Genetics-2006]
  5. Drummond DA, Raval A, and Wilke CO. A single determinant dominates the rate of yeast protein evolution. Mol Biol Evol 2006 Feb; 23(2) 327-37. doi:10.1093/molbev/msj038 pmid:16237209. PubMed HubMed [Drummond-MBE-2006]
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  6. Drummond DA, Bloom JD, Adami C, Wilke CO, and Arnold FH. Why highly expressed proteins evolve slowly. Proc Natl Acad Sci U S A 2005 Oct 4; 102(40) 14338-43. doi:10.1073/pnas.0504070102 pmid:16176987. PubMed HubMed [Drummond-PNAS-2005b]
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  7. Wilke CO, Bloom JD, Drummond DA, and Raval A. Predicting the tolerance of proteins to random amino acid substitution. Biophys J 2005 Dec; 89(6) 3714-20. doi:10.1529/biophysj.105.062125 pmid:16150971. PubMed HubMed [Wilke-BiophysJ-2005]
  8. Drummond DA, Iverson BL, Georgiou G, and Arnold FH. Why high-error-rate random mutagenesis libraries are enriched in functional and improved proteins. J Mol Biol 2005 Jul 22; 350(4) 806-16. doi:10.1016/j.jmb.2005.05.023 pmid:15939434. PubMed HubMed [Drummond-JMB-2005]
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  9. Drummond DA, Silberg JJ, Meyer MM, Wilke CO, and Arnold FH. On the conservative nature of intragenic recombination. Proc Natl Acad Sci U S A 2005 Apr 12; 102(15) 5380-5. doi:10.1073/pnas.0500729102 pmid:15809422. PubMed HubMed [Drummond-PNAS-2005a]
  10. Bloom JD, Silberg JJ, Wilke CO, Drummond DA, Adami C, and Arnold FH. Thermodynamic prediction of protein neutrality. Proc Natl Acad Sci U S A 2005 Jan 18; 102(3) 606-11. doi:10.1073/pnas.0406744102 pmid:15644440. PubMed HubMed [Bloom-PNAS-2005]
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All Medline abstracts: PubMed HubMed